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Hotels near SPIN San Francisco in San Francisco

Choose among 352 hotels near SPIN San Francisco in San Francisco

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8.4
Great53 reviews
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1.7 km from City Centre400 m from SPIN San Francisco
Set at 500 metres from San Francisco Museum of Modern Art, the 4-star Canopy By Hilton San Francisco Soma overlooks the city and invites guests to have a drink at a coffee bar.
From£ 140 /nightSelect
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2.4 km from City Centre500 m from SPIN San Francisco
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2.4 km from City Centre500 m from SPIN San Francisco
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2.4 km from City Centre500 m from SPIN San Francisco
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8.4
Great662 reviews
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1.9 km from City Centre500 m from SPIN San Francisco
Featuring fitness classes, massage therapy and recreational facilities, the sophisticated 4-star Hyatt Regency San Francisco Downtown Soma is about 5 minutes' drive from Pier 39.
From£ 113 /nightSelect
8.4
Great765 reviews
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1.7 km from City Centre500 m from SPIN San Francisco
Featuring American cuisine and an indoor swimming pool, the 39-story smoke-free Marriott Marquis Union Square is located near an underground station and 25 minutes' walk from Coit Tower.
From£ 69 /nightSelect
MarriottHotel
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1.7 km from City Centre500 m from SPIN San Francisco
Featuring an indoor pool, the Marriott is set merely a 5-minute walk from Yerba Buena Gardens and San Francisco Museum of Modern Art.
From£ 324 /nightSelect
8.4
Great392 reviews
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2.2 km from City Centre600 m from SPIN San Francisco
Providing a hot tub and an indoor pool, the contemporary Palace Hotel, A Luxury Collection Hotel, is set 5 minutes' walk from San Francisco Museum of Modern Art and near a tube station.
From£ 166 /nightSelect
8.4
Great738 reviews
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1.7 km from City Centre600 m from SPIN San Francisco
Placed in the Downtown San Francisco district, the historical Mosser San Francisco is conveniently situated within 6 km of Alcatraz Island.
From£ 49 /nightSelect
8.0
Great99 reviews
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2.0 km from City Centre600 m from SPIN San Francisco
Comprising 12 rooms in the very heart of San Francisco, the smoke-free Utah Inn lies 20 minutes' walk from Grace Cathedral.
From£ 42 /nightSelect
8.4
Great192 reviews
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1.8 km from City Centre600 m from SPIN San Francisco
The sophisticated Four Seasons Hotel San Francisco features an American restaurant together with sauna facilities and an indoor pool, boasting an ideal location near a bus stop.
From£ 35 /nightSelect
8.4
Great403 reviews
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1.5 km from City Centre600 m from SPIN San Francisco
Set 450 metres of Metreon, the upscale Intercontinental San Francisco, An Ihg San Francisco boasts fitness classes, various recreational opportunities and entertainment activities.
From£ 153 /nightSelect
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1.5 km from City Centre600 m from SPIN San Francisco
This 59 m² property in San Francisco is situated a short stroll from Yerba Buena Ice Skating and Bowling Center and a 10-minute walk from Powell Street underground station.
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1.5 km from City Centre600 m from SPIN San Francisco
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1.5 km from City Centre600 m from SPIN San Francisco
The Soma 1Br W Wd Gym Roofdeck Nr Muni Bart Sfo-273 is nestled right in the centre of San Francisco and nearly 20 minutes' walk from Chinatown.
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1.5 km from City Centre600 m from SPIN San Francisco
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1.5 km from City Centre700 m from SPIN San Francisco
The Soma 1Br W Gym Roofdeck Wd Nr Muni Bart Sfo-272 is set right in the centre of San Francisco and about 10 minutes' walk from Powell Street underground station.
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1.5 km from City Centre700 m from SPIN San Francisco
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2.7 km from City Centre700 m from SPIN San Francisco
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2.7 km from City Centre700 m from SPIN San Francisco
Set 5 minutes by car from Oracle Park, the Rincon Hill Studio W Gym Bbq Wd Nr Sv Sfo-240 San Francisco lies in the South of Market (SOMA) district.
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2.7 km from City Centre700 m from SPIN San Francisco
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8.2
Great713 reviews
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1.4 km from City Centre700 m from SPIN San Francisco
The 3-star Pickwick Hotel is situated in the downtown Downtown San Francisco district, 22 minutes' drive from San Francisco International airport.
From£ 84 /nightSelect
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2.0 km from City Centre700 m from SPIN San Francisco
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5.0
Guest rating1 review
The largest option:
4 adults
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2.8 km from City Centre800 m from SPIN San Francisco
The surrounding area includes Ferry Building, nearly a 10-minute walk away, and Embarcadero tube station about a 10-minute walk from the 42-story Oakwood At 399 Fremont.
From£ 197 /nightSelect
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2.1 km from City Centre800 m from SPIN San Francisco
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1.3 km from City Centre800 m from SPIN San Francisco
From£ 191 /nightSelect
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1.3 km from City Centre800 m from SPIN San Francisco
The Soma 1Br W Rooftop Bbq Concierge Nr Bart Sfo-1431 is a perfect vacation spot around 10 minutes by car from Pier 39 and other San Francisco landmarks.
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1.3 km from City Centre800 m from SPIN San Francisco
Guests of this 1-bedroom property will benefit from the location in San Francisco, as Union Square is only 11 minutes' walk away.
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1.3 km from City Centre800 m from SPIN San Francisco
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8.4
Great377 reviews
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2.2 km from City Centre800 m from SPIN San Francisco
There are rooms facing city and the 4-star Galleria Park is set a mere 0.6 km from Union Square.
From£ 103 /nightSelect
8.4
Great263 reviews
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1.6 km from City Centre800 m from SPIN San Francisco
While staying at the 4-star Citizenm San Francisco Union Square you are invited to discover Pier 39, set about a 10-minute drive away, or Contemporary Jewish Museum, which is just 900 metres away.
From£ 108 /nightSelect
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2.8 km from City Centre800 m from SPIN San Francisco
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2.8 km from City Centre800 m from SPIN San Francisco
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2.8 km from City Centre800 m from SPIN San Francisco
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Hotel 964Hotel
8.6
Great30 reviews
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1.3 km from City Centre800 m from SPIN San Francisco
The 2-star 964 San Francisco is nearly a 17-minute walk from Chinatown and has a quick access to Orpheum Theatre.
From£ 139 /nightSelect
8.0
Great288 reviews
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1.3 km from City Centre800 m from SPIN San Francisco
Located a 25-minute walk from Painted Ladies, accessible by an underground station, you may exterior conceals the smoke-free Hampton Inn San Francisco Downtown/Convention Center with 174 comfortable guest rooms and a snack bar.
From£ 111 /nightSelect
7.8
Very good211 reviews
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1.4 km from City Centre800 m from SPIN San Francisco
Situated in a market area, the 3-star Bay Bridge offers quick access to San Francisco International airport within 21 minutes' drive.
From£ 92 /nightSelect
8.4
Great280 reviews
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1.6 km from City Centre800 m from SPIN San Francisco
Offering fitness classes and various recreational opportunities, the boutique style Union Square San Francisco is merely 5 minutes' walk from Powell Street subway station and provides easy access to Ferry Building Market.
From£ 106 /nightSelect
8.2
Great584 reviews
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1.5 km from City Centre800 m from SPIN San Francisco
Located relatively close to Union Square Park, the pleasant Axiom San Francisco features an à la carte restaurant and fitness classes and entertainment activities.
From£ 61 /nightSelect
8.4
Great597 reviews
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1.5 km from City Centre900 m from SPIN San Francisco
Located approximately a 5-minute walk from Union Square, the elegant 3-star Abri San Francisco is about 9 minutes' walk from Yerba Buena Gardens.
From£ 94 /nightSelect
8.4
Great1122 reviews
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1.6 km from City Centre900 m from SPIN San Francisco
Featuring various recreational opportunities, entertainment activities and barbeque grills, the Herbert has a central setting within 7 minutes' walk of Chinatown.
From£ 150 /nightSelect
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2.8 km from City Centre900 m from SPIN San Francisco
Pier 39 is within 3.7 km of the S Beach Studio W 3 Pools Spa Facing The Water Sfo-93 San Francisco and Exploratorium is around 2.5 km away.
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2.8 km from City Centre900 m from SPIN San Francisco
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8.4
Great711 reviews
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1.7 km from City Centre900 m from SPIN San Francisco
The 2-star Stratford is situated in the very heart of San Francisco a mere 6 minutes on foot from Union Square.
From£ 83 /nightSelect
8.4
Great1004 reviews
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1.5 km from City Centre900 m from SPIN San Francisco
The lovely Fusion, A C-Two San Francisco features fitness classes and recreational facilities on site, and is situated in an entertainment neighbourhood a few blocks away from a cable car station.
From£ 61 /nightSelect
8.2
Great283 reviews
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2.4 km from City Centre900 m from SPIN San Francisco
Situated in the very heart of San Francisco and about a 25-minute stroll from Asian Art Museum, the comfortable 3-star Hyatt Place San Francisco/Downtown offers 230 rooms.
From£ 153 /nightSelect
Hotel IkonHotel
8.2
Great621 reviews
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2.0 km from City Centre900 m from SPIN San Francisco
Featuring various recreational opportunities and entertainment activities, the 2-star Ikon San Francisco is situated nearly 6 minutes' walk from Union Square and nearly 5 minutes' walk from Montgomery Street tube station.
From£ 71 /nightSelect
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2.9 km from City Centre900 m from SPIN San Francisco
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8.4
Great1216 reviews
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1.5 km from City Centre900 m from SPIN San Francisco
Thanks to its unique location, the 32-story Hilton Parc 55 San Francisco Union Square is at 450 metres of Union Square and near a tube station.
From£ 99 /nightSelect
7.8
Very good31 reviews
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1.2 km from City Centre900 m from SPIN San Francisco
There are rooms facing city and the Sunset Hotel - Downtown San Francisco is set within a 9-minute stroll of Children's Creativity Museum.
From£ 27 /nightSelect
7.8
Very good193 reviews
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1.2 km from City Centre900 m from SPIN San Francisco
The smoke-free Sunnyside Hotel-Downtown San Francisco features 29 rooms only a 5-minute walk from International Art Museum of America and a 10-minute walk from Powell Street.
From£ 35 /nightSelect
8.4
Great624 reviews
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2.1 km from City Centre900 m from SPIN San Francisco
The 32One is about a 12-minute walk from North Beach, boasting various recreational opportunities and entertainment activities.
From£ 89 /nightSelect
BaldwinHotel
7.0
Very good3 reviews
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2.1 km from City Centre900 m from SPIN San Francisco
Exploratorium is set nearly 20 minutes' walk from the 3-star Baldwin.
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8.2
Great56 reviews
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1.6 km from City Centre900 m from SPIN San Francisco
Featuring fitness classes, various recreational opportunities and entertainment activities, the 2-star Express San Francisco Union Square is situated within 7 minutes' walk of Market Street and within 5 minutes' walk of Powell Street tube station.
From£ 91 /nightSelect
8.4
Great181 reviews
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1.9 km from City Centre900 m from SPIN San Francisco
Set in a theatre district, nearly a 12-minute walk from Children's Creativity Museum, the prestigious 4-star Taj Campton Place San Francisco features rooms with a modern décor.
From£ 152 /nightSelect
8.2
Great7 reviews
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1.6 km from City Centre900 m from SPIN San Francisco
Asian Art Museum is nearly an 18-minute walk from the 2-star Pod Room O'Farrell St Union Square San Francisco, while Pier 39 is 10 minutes' drive away.
From£ 47 /nightSelect
8.0
Great299 reviews
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1.6 km from City Centre900 m from SPIN San Francisco
Located nearly 5 minutes on foot from Powell and Market Cable Car Turnaround, the The Bartlett Hotel And Guesthouse San Francisco has 67 rooms, and lies near an underground station.
From£ 56 /nightSelect
8.2
Great345 reviews
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2.1 km from City Centre900 m from SPIN San Francisco
The Des Arts is a lovely 2-star property set about 25 minutes' walk from Ghirardelli Square and about 25 minutes' walk from Pier 39.
From£ 48 /nightSelect
8.2
Great297 reviews
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2.1 km from City Centre900 m from SPIN San Francisco
Opened in 1918, the perfect 4-star Triton San Francisco welcomes guests in the financial district of San Francisco, boasting a central position near an underground station.
From£ 85 /nightSelect
Minna ExpressApartment
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1.2 km from City Centre900 m from SPIN San Francisco
Offering a kitchen with a microwave and a fridge, the venue is located 15 minutes' walking distance from the centre of San Francisco.
From£ 91 /nightSelect
8.4
Great474 reviews
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1.9 km from City Centre900 m from SPIN San Francisco
Featuring fitness classes and various recreational opportunities, the 36-story eco-friendly Grand Hyatt San Francisco Union Square is situated 5 minutes' walk from Union Square and a 10-minute walk from Powell Street tube station.
From£ 127 /nightSelect
8.0
Great272 reviews
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1.4 km from City Centre900 m from SPIN San Francisco
Placed within 8 minutes' stroll of the 2.6-acre public plaza "Union Square" and in the heart of San Francisco, the smoke-free Sonder At Found Union Square offers 73 rooms.
From£ 86 /nightSelect
8.2
Great524 reviews
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1.7 km from City Centre900 m from SPIN San Francisco
Located around 25 minutes' walk from Ferry Building and in front of a cable car station, the 31-story Westin St. Francis San Francisco On Union Square boasts 1195 rooms and an à la carte restaurant serving the American cuisine.
From£ 114 /nightSelect
8.4
Great433 reviews
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2.2 km from City Centre1000 m from SPIN San Francisco
The surrounding area includes Chinatown, only 450 metres away, and Montgomery Street tube station 750 metres from the comfortable Orchard Garden.
From£ 123 /nightSelect
8.2
Great149 reviews
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1.3 km from City Centre1000 m from SPIN San Francisco
10 minutes' drive from Oracle Park, the 3-star Metropolis includes 105 rooms.
From£ 89 /nightSelect
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2.9 km from City Centre1000 m from SPIN San Francisco
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Minna HotelHostel
8.0
Great529 reviews
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1.1 km from City Centre1000 m from SPIN San Francisco
Located less than 10 minutes' walk from Asian Art Museum, the 2-star Minna San Francisco has 72 rooms, and lies near an underground station.
From£ 65 /nightSelect
8.2
Great298 reviews
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2.1 km from City Centre1000 m from SPIN San Francisco
Located in a shopping district about 5 minutes' walk from Chinatown, the smoke-free Urban offers various recreational opportunities and entertainment activities.
From£ 63 /nightSelect
8.6
Great1242 reviews
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1.5 km from City Centre1000 m from SPIN San Francisco
The luxury Nikko has a swimming pool along with a cocktail bar and boasts a location not so far from Golden Gate Park.
From£ 138 /nightSelect
Hotel ViaHotel
8.4
Great66 reviews
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2.6 km from City Centre1000 m from SPIN San Francisco
Situated near a train station, the 4-star Via San Francisco is within a 5-minute stroll of Oracle Park Baseball Stadium.
From£ 235 /nightSelect
8.2
Great72 reviews
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1.3 km from City Centre1000 m from SPIN San Francisco
San Francisco Museum of Modern Art is approximately 10 minutes' walk from the Line.
From£ 197 /nightSelect
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1.9 km from City Centre1000 m from SPIN San Francisco
Featuring a fully furnished kitchen, the venue is only 1.6 km from Contemporary Jewish Museum.
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8.4
Great1037 reviews
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1.6 km from City Centre1000 m from SPIN San Francisco
Set nearly 6 minutes' walk from Market Street and in the Downtown San Francisco district of San Francisco, the welcoming Handlery Union Square has 377 rooms.
From£ 69 /nightSelect
8.2
Great213 reviews
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2.1 km from City Centre1000 m from SPIN San Francisco
Placed approximately 5 minutes on foot from Chinatown and in the very heart of San Francisco, the 2-star Sf Plaza offers 58 rooms.
From£ 69 /nightSelect
8.4
Great151 reviews
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2.5 km from City Centre1000 m from SPIN San Francisco
A central location of the welcoming Four Seasons Hotel San Francisco At Embarcadero provides easy access to the neo-gothic Grace Cathedral, which is merely 1.2 km away.
From£ 320 /nightSelect
7.4
Very good3 reviews
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2.5 km from City Centre1000 m from SPIN San Francisco
While staying at the 5-star Mandarin Oriental you are invited to discover Asian Art Museum, set nearly 20 minutes' walk away, or Alcatraz Island, which is 10 minutes away by car.
From£ 411 /nightSelect
Soma LoftsApartment
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1.2 km from City Centre1000 m from SPIN San Francisco
Nestled in Civic Center district of San Francisco, the venue is about 20 km from Oakland International airport.
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2.8 km from City Centre1000 m from SPIN San Francisco
Situated in the Embarcadero (North Waterfront) district, this spacious accommodation consists of 2 bedrooms, 2 bathrooms and a full kitchen.
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2.8 km from City Centre1000 m from SPIN San Francisco
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2.8 km from City Centre1000 m from SPIN San Francisco
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2.8 km from City Centre1000 m from SPIN San Francisco
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2.8 km from City Centre1000 m from SPIN San Francisco
Children's Creativity Museum is at an 11 km distance from the Waterfront S Beach 2Br W Pool Tennis Spa Sfo-426 San Francisco and Pier 39 is approximately 10 minutes away by car.
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2.8 km from City Centre1000 m from SPIN San Francisco
A fully furnished kitchen and a microwave and kitchenware are provided at this 62 m² apartment, which is located in the Embarcadero (North Waterfront) district, near Giants Stadium.
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2.8 km from City Centre1000 m from SPIN San Francisco
This 60 m² apartment gives direct access to Pac-Bell Stadium and comprises 1 bedrooms.
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2.8 km from City Centre1000 m from SPIN San Francisco
Union Square can be reached in 5 minutes' drive from this spacious apartment with 1 bedrooms, a fully-fitted kitchen, and 1 bathrooms.
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2.8 km from City Centre1000 m from SPIN San Francisco
Set steps from Oracle Park, this spacious apartment comes with 1 bedrooms and a full kitchen.
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2.8 km from City Centre1000 m from SPIN San Francisco
The South Beach 2Br W Pool Tennis Spa Sfo-1400 San Francisco is nestled in the Embarcadero (North Waterfront) district, Fisherman's Wharf is 10 minutes' drive away.
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2.8 km from City Centre1000 m from SPIN San Francisco
Offering 1 bedrooms and 1 bathrooms, this apartment is set only 150 metres from Giants Stadium.
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2.8 km from City Centre1000 m from SPIN San Francisco
The Waterfront S Beach 1Br W Pool Tennis Spa Sfo-423 San Francisco is set within 3.9 km of Fisherman's Wharf and 1.8 km from Ferry Building.
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8.4
Great1152 reviews
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2.0 km from City Centre1000 m from SPIN San Francisco
Located in the very heart of the city, approximately an 8-minute walk from Chinatown, the Palihotel San Francisco offers 82 luxurious rooms.
From£ 89 /nightSelect
8.6
Great178 reviews
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1.5 km from City Centre1000 m from SPIN San Francisco
While staying at the eco-friendly Hi San Francisco Downtown you are invited to discover the east–west Lombard Street, set around 2.3 km away, or War Memorial Opera House, which is a 5-minute ride away.
From£ 38 /nightSelect
8.0
Great73 reviews
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1.1 km from City Centre1000 m from SPIN San Francisco
Offering a barber shop and storage for belongings, the Haveli Hotel - Downtown Market lies in the Downtown San Francisco district of San Francisco, about 10 minutes' drive from Fisherman's Wharf and 5 minutes by car from Exploratorium.
From£ 38 /nightSelect
8.6
Great1006 reviews
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1.8 km from City Centre1000 m from SPIN San Francisco
Located less than a 5-minute stroll from Union Square in the theatre Downtown San Francisco district, the lovely Chancellor Hotel On Union Square San Francisco features 126 rooms along with entertainment activities and various recreational opportunities.
From£ 103 /nightSelect
8.6
Great6 reviews
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1.6 km from City Centre1000 m from SPIN San Francisco
The Frank enjoys a perfect location in the heart of San Francisco, within a 10-minute stroll of Cable Car Museum.
From£ 264 /nightSelect
8.2
Great49 reviews
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1.1 km from City Centre1000 m from SPIN San Francisco
The Desmond, located a 5-minute walk from Westfield San Francisco Centre, is also at a proximity to Powell and Market Cable Car Turnaround.
From£ 58 /nightSelect
8.4
Great523 reviews
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1.6 km from City Centre1000 m from SPIN San Francisco
Comprising 153 rooms, the 3-star King George is set within walking distance from the theatre district of San Francisco, approximately a 10-minute drive from Lombard Street.
From£ 56 /nightSelect
8.4
Great557 reviews
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1.8 km from City Centre1000 m from SPIN San Francisco
About 5 minutes on foot from Curran Theatre, the 4-star Beacon Grand A Union Square offers a lounge bar together with fitness classes, massage therapy and live entertainment.
From£ 105 /nightSelect
8.4
Great301 reviews
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1.6 km from City Centre1000 m from SPIN San Francisco
The 4-star G is nestled within walking distance to the theatre district of San Francisco, about 6 minutes' walk from Xanadu Gallery.
From£ 86 /nightSelect
8.0
Great6 reviews
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2.0 km from City Centre1000 m from SPIN San Francisco
The positioning of the Worldmark Hotel, in the heart of San Francisco ensures fast access to San Francisco Playhouse, which is nearly a 6-minute walk away.
From£ 153 /nightSelect
8.0
Great263 reviews
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1.9 km from City Centre1000 m from SPIN San Francisco
Located only a 5-minute walk from Union Square, the 30-story Marriott Union Square features 401 rooms with views of the bay.
From£ 105 /nightSelect

FAQs about hotels near SPIN San Francisco

Our FAQs contain 9 questions about hotels close to SPIN San Francisco.

What are the best budget hotels to book near SPiN San Francisco?

Due to HotelMix.co.uk travel statistics, Days Inn By Wyndham San Francisco - Lombard along with King George are the most popular budget hotels providing complimentary private parking and free parking near SPiN San Francisco.

What are the top-rated SPiN San Francisco accommodations to stay in?

If you want to discover Downtown San Francisco, consider booking Stanford Court which offers a tennis court, a sauna and a health club, and set within 1.3 km from SPiN San Francisco.

What are the top SPiN San Francisco hotels with free parking?

Some of the best properties near SPiN San Francisco with free parking are Redwood Inn and Best Western Red Coach Inn. Other boutique hotels in San Francisco you can check here.

What are the top hotels next to SPiN San Francisco for couples?

Adante Hotel and Hotel Whitcomb are the best private hotels in San Francisco for a romantic stay close to SPiN San Francisco.

What family hotels near SPiN San Francisco would you recommend?

Among 35 hotels, the best option for a family stay is Galleria Park Hotel, which is set 0.8 km from SPiN San Francisco.

Do any hotels near SPiN San Francisco in San Francisco offer free breakfast?

You can enjoy free breakfast by booking The Andrews Hotel, which is situated about 1.2 km from SPiN San Francisco.

What are the best hotels next to SPiN San Francisco allowing pets?

Hotel Diva and Kimpton Buchanan Hotel are the top pet-friendly accommodations to stay close to SPiN San Francisco with your favoured ones. Other suitable options check here.

What are the best luxury hotels near SPiN San Francisco?

If you're searching for a luxury stay next to SPiN San Francisco, consider booking San Francisco Marriott Marquis with room rates from 144£ per night.

What are the top hotels near SPiN San Francisco providing a swimming pool?

If you want to relax around the pool, stay at Holiday Inn Golden Gateway or Carriage Inn, which are the best options among 7 hotels near SPiN San Francisco.

Hotels near SPIN San Francisco in San Francisco

Hotels close to SPIN San Francisco in San Francisco

The Donatello Hotel and Gaylord Suites are examples of some accommodation options that are local to this special site. There are 99 available hotels within short distance from this attraction. Visitors looking to stay near SPiN San Francisco will choose from 9 hotels available in the centre of San Francisco, such as The Mosser and Courtyard By Marriott San Francisco Downtown. Hotels near SPiN San Francisco in San Francisco offer prices at 81£ per night.

Luxury San Francisco hotels near SPIN San Francisco

Hotels near SPiN San Francisco include such chic hotels as Axiom Hotel, and Intercontinental San Francisco. If these hotels aren't what you're looking for, try "Property Offline" - Hasan or The Andrews Hotel to benefit from reliable service and be close to SPiN San Francisco. In San Francisco, Union Square district is home to several hotels including the 4-star Hotel Spero, a distinctive boutique hotel.

Cheap hotels near SPIN San Francisco from 15 GBP

If you prefer budget accommodations in San Francisco, there are 95 options to consider, such as Lombard Plaza Motel with rates at 127£ or The Adrian for 68£ per night. For budget hotels near this sight, look at SPiN San Francisco and SPiN San Francisco.

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Hotels near SPIN San Francisco essential information

🏨 Hotels near SPIN San Francisco 352
👛 Lowest price 15 GBP
✍️ Hotels Reviews 87 978
Guest reviews of hotels in San Francisco